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Nattokinase is renowned for its ability to dissolve spike proteins, reduce blood clots, enhance cardiovascular health, support immune function, and more.

As strong supporters of Nattokinase, we've researched the top supplements to help health-conscious individuals make informed choices for better health.

We are independent doctors and healthcare providers.

While Big Pharma chases profits, we seek real healthcare solutions, prioritizing patients over profits. After extensive research in Japan, our founders uncovered the power of natto and brought it to the United States, along with unbiased reviews.  Our expert physicians deliver the best research — and products — available.

We evaluated nattokinase products based on four key criteria

1
We prioritized fibrinolytic units (FUs), which measure nattokinase’s ability to break down fibrin.
2
Products with supporting ingredients like dandelion root, selenium, and Irish sea moss, were upgraded.
3
We assessed tolerability, favoring vegetarian, non-GMO, and gluten-free options.
4
Price per FU was used to determine cost effectiveness, or value.

Using this criteria, we identified the best nattokinase products based on efficacy, formulation, and affordability.

Our Winner

  • The most fibrinolytic units (FUs) of nattokinase per serving
  • Synergistic blend of ingredients
  • Highest quality ingredients
  • Great value for the amount of nattokinase and supporting ingredients

$89.99

for a one-month supply
(or less with a TWC Membership)

Get Spike Support Formula directly from The Wellness Company.

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Runners Up

About Nattokinase

Source
Nattokinase is a potent enzyme derived from natto, a traditional Japanese food made by fermenting soybeans with Bacillus subtilis natto. This fermentation process enhances the enzyme’s fibrinolytic properties, making it an effective natural remedy for circulatory health. It has been consumed in Japan for centuries for its cardiovascular benefits.
Benefits
Nattokinase supports heart health by promoting blood circulation and clot breakdown. It may help reduce the risk of blood clots, lower blood pressure, and enhance overall vascular function. Additionally, nattokinase has been studied for its potential to improve blood flow, decrease arterial stiffness, and support cognitive function by preventing micro clots in the brain.
Spike Detox
Recent research suggests nattokinase may aid in the breakdown of spike proteins associated with viral infections and mRNA-based therapies. Its enzymatic activity appears to degrade harmful proteins that may contribute to clotting and inflammation. This property has made nattokinase a subject of interest in post-viral recovery and detoxification strategies.Metric description
Cholesterol
Nattokinase helps regulate cholesterol levels by reducing LDL oxidation and supporting vascular elasticity. It enhances lipid metabolism, which may contribute to lower total cholesterol and triglyceride levels. Some studies indicate it works synergistically with other heart-healthy nutrients to improve lipid profiles and protect against atherosclerosis-related conditions.
Fibrinolytic
Nattokinase exhibits potent fibrinolytic activity. In other words, it effectively dissolves fibrin, a protein involved in blood clot formation. By breaking down excess fibrin, it helps maintain smooth blood flow and reduces the risk of thrombosis. This property makes nattokinase valuable for stroke prevention, deep vein thrombosis, and overall cardiovascular support.

ABOUT
NATTOKINASE

Source
Nattokinase is a potent enzyme derived from natto, a traditional Japanese food made by fermenting soybeans with Bacillus subtilis natto. This fermentation process enhances the enzyme’s fibrinolytic properties, making it an effective natural remedy for circulatory health. It has been consumed in Japan for centuries for its cardiovascular benefits.
Benefits
Nattokinase supports heart health by promoting blood circulation and clot breakdown. It may help reduce the risk of blood clots, lower blood pressure, and enhance overall vascular function. Additionally, nattokinase has been studied for its potential to improve blood flow, decrease arterial stiffness, and support cognitive function by preventing micro clots in the brain.
Spike Detox
Recent research suggests nattokinase may aid in the breakdown of spike proteins associated with viral infections and mRNA-based therapies. Its enzymatic activity appears to degrade harmful proteins that may contribute to clotting and inflammation. This property has made nattokinase a subject of interest in post-viral recovery and detoxification strategies.Metric description
Cholesterol
Nattokinase helps regulate cholesterol levels by reducing LDL oxidation and supporting vascular elasticity. It enhances lipid metabolism, which may contribute to lower total cholesterol and triglyceride levels. Some studies indicate it works synergistically with other heart-healthy nutrients to improve lipid profiles and protect against atherosclerosis-related conditions.
Fibrinolytic
Nattokinase exhibits potent fibrinolytic activity. In other words, it effectively dissolves fibrin, a protein involved in blood clot formation. By breaking down excess fibrin, it helps maintain smooth blood flow and reduces the risk of thrombosis. This property makes nattokinase valuable for stroke prevention, deep vein thrombosis, and overall cardiovascular support.

OUR WINNER

The Wellness Company is an emerging business that has earned the trust of over 34,000 customers through its comprehensive approach, unique formulas developed by top U.S. physicians, and products made from high-quality, pure ingredients.

We recommend visiting their website, where you can find other supplements to support a healthy lifestyle, along with telemedicine memberships at affordable prices, and their flagship emergency kits containing medications that are difficult to obtain even from your doctor.

Shop now →

Nattokinase in the News

Dr. Drew and Dr. Heather Gessling on the benefits of Nattokinase

Dr. Robert Malone speaks on Nattokinase

Dr. Peter McCullough and Dr. Ryan Cole on Nattokinase

"Studies show that nattokinase dissolves blood clots — which helps maintain good blood vessel structure, improves blood flow, and lowers the risk of heart disease."

"Nattokinase...a type of enzyme that helps dissolve blood clots."

Nattokinase is a thrombolytic, spike-protein degradative and anti-aging enzyme produced by Bacillus subtilis.

"The ability of nattokinase to degrade amyloid fibrils is quite promising," says Li Gan, an Alzheimer’s expert at the Gladstone Institute for Neurological Disease.

“Nattokinase has the ability to get into the blood stream and can directly destroy blood clots, thin the blood and improve blood flow,” says Dr. Kevin Wang, associate professor of molecular biology at Northeastern State University, “It cleans out the blood vessels, reducing the risk of hypertension and stroke and can also reduce the risk of heart attack.”

"Nattokinase decreases platelet aggregation and thrombus formation in a dose-dependent fashion both in vitro and in vivo"